NORTH-TO-SOUTH POSITION OF MISSISSIPPI RIVER STATES AND THEIR HEALTH RANK: A COMMENTARY John Hart Sherman Chiropractic College, Spartanburg, South Carolina 29304 The recent news that Minnesota ranks first in health and Louisiana last, suggested to the author that their connecting medium, the Mississippi River, might be a factor. Consequently, a correlation was sought between position of states along the Mississippi River and their health rank. Correlations were sought in similar categories such as position of states along the eastern U.S. seaboard and Missouri River. Accordingly, each state was ranked according to its north-to-south position. The position rank was then correlated with the health rank for the years 2004, 2005, and 2006 using the Spearman correlation test. Similar correlations were also made for Mississippi River states and temperature, per capita income, and ACT scores. A strong correlation was found between position of states along the Mississippi River and their health rank for the years assessed (mean r = 0.959). Strong correlations were also found for position of Mississippi River states and temperature (r = 0.976), per capita income (r = -0.952), and ACT scores (mean r = -0.863). Correlations were less strong when comparing health rank to state positions along the eastern seaboard (mean r = 0.859) and along the Missouri River (mean r = 0.458). Thus, a state’s north-to-south position, particularly along the Mississippi River, appears to be a risk factor for its health rank. Further study is indicated regarding possible causative mechanisms. Keywords: Mississippi River, river contaminants, health rank of states, per capita income, ACT scores, and temperature 6