SWIMMING AGAINST THE TIDE: EFFORTS TO RECOVER FRESHWATER MUSSELS FROM THE THREAT OF EXINCTION. Kurt I. Welke1, Todd Turner2, Roger Gordon2, and Pam Thiel3. 1Wisconsin Department of Natural Resources, Fitchburg, WI 53711 2U.S. Fish and Wildlife Service, Genoa National Fish Hatchery, Genoa WI 54632 3U.S. Fish and Wildlife Service, LaCrosse FRO, Onalaska, WI 54650. Freshwater Mussels (Unionidae) are recognized as North Americas most seriously imperiled fauna. Approximately 67% of the 300 recognized species are designated as vulnerable to extinction or already extinct. The rate of loss has accelerated rapidly within the last 50 years as the effects of impoundment, sedimentation, channelization, dredging and water pollution have manifested themselves acutely and chronically. Currently, the zebra mussel (Dreissena polymorpha) threatens to eliminate already weakened populations, a fact legally affirmed by the issuance of a jeopardy opinion on the continued operation and maintenance of the Mississippi River 9-foot navigation project. In early 2000, a cooperative effort was initiated by personnel from the WDNR and USFWS to prevent the extinction of the federally listed Higgins Eye Pearly Mussel (Lampsilis higginsi). Juvenile mussels were propagated at the Genoa National Fish Hatchery using standard mass infection procedures on largemouth bass (Micropterus salmoides) and walleye (Stizostedion vitreum) host fish. Culturing of juveniles occurred in 4 differing treatments to identify factors that contributed to optimal survival and growth. Mussels were successfully stocked into recipient habitats in summer/fall 2000. The effort will be continued and expanded in 2001. Keywords: mussels, recovery, propagation